Statin therapy for primary prevention
نویسندگان
چکیده
منابع مشابه
Statin therapy for primary prevention of cardiovascular disease.
CLINICAL QUESTION Do statins reduce rates of cardiovascular events when used for primary prevention? BOTTOM LINE When used for primary prevention, statins are associated with lower rates of all-cause mortality, major vascular events, and revascularizations compared with placebo. Statin therapy is not associated with increased rates of life-threatening adverse effects such as cancer.
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BACKGROUND AND PURPOSE Statins are widely used to reduce the risk of stroke in patients with coronary artery disease (CAD), but less so in patients without CAD. We reviewed recent trials for new evidence for the reduction in risk of stroke. SUMMARY OF REVIEW In patients with CAD, moderate-intensity statin treatment has been associated with reductions in risk of stroke, with no increase in hem...
متن کاملCost-effectiveness of statin therapy for primary prevention in a low-cost statin era.
BACKGROUND With wide availability of low-cost generics, primary prevention with statins has become less expensive. We projected the cost-effectiveness of expanded statin prescribing strategies using low-cost generics and identified conditions under which aggressive prescribing ceases to be cost-effective. METHODS AND RESULTS We simulated expanded statin prescribing strategies with the coronar...
متن کاملHealth Services and Outcomes Research Cost-Effectiveness of Statin Therapy for Primary Prevention in a Low-Cost Statin Era
Background—With wide availability of low-cost generics, primary prevention with statins has become less expensive. We projected the cost-effectiveness of expanded statin prescribing strategies using low-cost generics and identified conditions under which aggressive prescribing ceases to be cost-effective. Methods and Results—We simulated expanded statin prescribing strategies with the coronary ...
متن کاملTough questions about the value of statin therapy for primary prevention: did JUPITER miss the moon?
An unusually rancorous debate that was recently described by the president of the American Heart Association as “a statistical tug-of-war” has raised more questions than answers about the risks and benefits of statins in primary prevention. Spending money to save money seemed like a reasonable strategy in lowering serum lipids in primary prevention of adverse cardiovascular outcomes, particular...
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ژورنال
عنوان ژورنال: Nature Reviews Cardiology
سال: 2009
ISSN: 1759-5002,1759-5010
DOI: 10.1038/nrcardio.2009.134